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초록정보 내용
Objectives
This systematic review aimed to evaluate the therapeutic effects and safety of Chuna and manual therapies for children with nocturnal crying by analyzing randomized controlled trials (RCTs).
Methods
A literature search was conducted in May 2025 using databases including PubMed, CAJ, KISS, RISS, and OASIS. RCTs that investigated the effects of Chuna or manual therapy in children with nocturnal crying were selected. A total of 13 studies met the inclusion criteria. Meta-analysis and risk of bias assessment were conducted, and the interventions and clinical outcomes were systematically analyzed.
Results
Thirteen RCTs were included, mostly targeting infants and toddlers. Treatment durations ranged from 4 days to 4 weeks, with the majority of studies applying short-term treatment within 7 days. The most common treatment frequency was once daily. Among the included studies, 11 applied Chuna or manual therapy based on Korean medicine focusing on meridian and acupoint stimulation, one applied chiropractic therapy, and one osteopathic treatment characterized by light touch and muscle relaxation. Risk of bias assessment showed that most studies had a low risk. Overall, Chuna and manual therapies demonstrated statistically significant improvements in clinical outcomes such as increased sleep duration, reduced frequency of crying, and improvement in symptom scores compared to control groups. A meta-analysis of two studies comparing Chuna to herbal medicine revealed that Chuna was significantly more effective with low heterogeneity. Adverse events were mostly unreported or mild.
Conclusions
This systematic review of 13 RCTs suggests that Chuna and manual therapies may be safe and effective non-pharmacological interventions for nocturnal crying in infants and young children. These therapies can be a useful option for patients with limited use of medication. Further rigorous clinical studies are needed to strengthen the evidence base and refine treatment protocols.
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